发表论文

Tong C, Min PX, Zhang Q, Gu RX, Wen YH, ShiY, Bao YH, Chen X, Zhang YX, Mao XF, Yuan HY, Liu XX, Sasaki T, Zhang L*,Han F*, Lu YM*.

Striatal CDK5 Regulates Cholinergic NeuronActivation and Dyskinesia-like Behaviors through BK Channels.

Research (Wash D C). 2023 Apr 18;6:0121.

doi: 10.34133/research.0121. eCollection2023.


发表日期:2023

Lu YP, Chen X, Liu XX, Shi Y, Wei ZC, Feng LL, Jiang Q, Ye WF, Sasaki T, Fukunaga K, Ji Y, Han F*, Lu YM*.

Endothelial TFEB signaling mediated autophagic disturbance initiates microglial activation and cognitive dysfunction.

Autophagy. 2023 Jan 1;1-18.

doi: 10.1080/15548627.2022.2162244.


发表日期:2023

Luo YF#, Lu L#, Song HY, Xu H, Zheng ZW, Wu ZY, Jiang CC, Tong C, Yuan HY, Liu XX, Chen X, Sun ML, Tang YM, Fan HY, Han F*, Lu YM*.

Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors.

Mol Psychiatry. 2023 Jan 23.

doi: 10.1038/s41380-023-01954-y.

发表日期:2023

Liu XX, Chen XH, Zheng ZW, Jiang Q, Li C, Yang L, Chen X, Mao XF, Yuan HY, Feng LL, Jiang Q, Shi WX, Sasaki T, Fukunaga K, Chen Z, Han F*, Lu YM*

BOD1 regulates the cerebellar IV/V lobe-fastigial nucleus circuit associated with motor coordination.

Signal Transduct Target Ther. 2022 Jun 1;7(1):170.  

doi: 10.1038/s41392-022-00989-x (IF=38.104)


发表日期:2022

Chen DY#, Sun NH#, Chen X, Gong JJ, Yuan ST, Hu ZZ, Lu NN, Körbelin J, Fukunaga K, Liu QH*, Lu YM*, Han F*.

Endothelium-derived semaphorin 3G attenuates ischemic retinopathy by coordinating β-catenin-dependent vascular remodeling

J Clin Invest. 2021 Feb 15;131(4):135296 

doi: 10.1172/JCI135296(IF=14.808)

发表日期:2021

Sun ML#, Mao XF#, Li ZM#, Zhu ZH, Gong DM, Lu L, Chen X, Zhang Y, Fukunaga K, Ji Y, Gu AH*, Lu YM*, Han F*. 

Endothelial peroxynitrite causes disturbance of neuronal oscillations by targeting caspase-1 in the arcuate nucleus.

Redox Biol. 2021 Nov;47:102147. 

doi: 10.1016/j.redox.2021.102147 (IF=11.799) 


发表日期:2021

Meng L, Wang C, Lu Y, Sheng G, Yang L, Wu Z, Xu H, Han C, Lu Y*, Han F*.

Targeted Regulation of Blood-Brain Barrier for Enhanced Therapeutic Efficiency of Hypoxia-Modifier Nanoparticles and Immune Checkpoint Blockade Antibodies for Glioblastoma

ACS Appl Mater Interfaces. 2021 Mar 17;13(10):11657-11671 

doi: 10.1021/acsami.1c00347(IF=9.229)

发表日期:2021

Xu H, Sheng G, Lu L, Wang C, Zhang Y, Feng L, Meng L, Min P, Zhang L, Wang Y, Han F*.

GRPr-mediated photothermal and thermodynamic dual-therapy for prostate cancer with synergistic anti-apoptosis mechanism

Nanoscale. 2021 Feb 25;13(7):4249-4261 

doi: 10.1039/d0nr07196j(IF=7.79)

发表日期:2021

Taleb A, Zhou YP, Meng LT, Zhu MY, Zhang Q, Naveed M, Li LD, Wang P, Zhou QG, Meng F, Han F*.

New application of an old drug proparacaine in treating epilepsy via liposomal hydrogel formulation

Pharmacol Res. 2021 Jul;169:105636 

doi: 10.1016/j.phrs.2021.105636(IF=7.658)

发表日期:2021

Liu XX#, Yang L#, Shao LX, He Y, Wu G, Bao YH, Lu NN, Gong DM, Lu YP, Cui TT, Sun NH, Chen DY, Shi WX, Fukunaga K, Chen HS, Chen Z*, Han F*, Lu YM*.

Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis

J Exp Med. 2020 Jan 6;217(1):e20180992

doi: 10.1084/jem.20180992(IF=14.307)


发表日期:2020

Sun NH#, Chen DY#, Ye LP, Sheng G, Gong JJ, Chen BH, Lu YM*, Han F*.

CRISPR-Sunspot: Imaging of endogenous low-abundance RNA at the single-molecule level in live cells

Theranostics. 2020 Sep 2;10(24):10993-11012 

doi: 10.7150/thno.43094(IF=11.556)


发表日期:2020

Sun ML, Chen X, Yin YX, Gao Y, Zhang L, Chen B, Ji Y, Fukunaga K, Han F*, Lu YM*.

Role of pericyte-derived SENP1 in neuronal injury after brain ischemia

CNS Neurosci Ther. 2020 Aug;26(8):815-828 

doi: 10.1111/cns.13398(IF=5.243)

发表日期:2020

Shao LX#, Jiang Q#, Liu XX#, Gong DM, Yin YX, Wu G, Sun NH, Wang CK, Chen QZ, Yu C, Shi WX, Fan HY, Fukunaga K, Chen Z*, Lu YM*, Han F*.

Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons

Mol Psychiatry. 2019 Oct;24(10):1461-1477

doi:10.1038/s41380-019-0402-8(IF=12.384)


发表日期:2019

Tan C#, Lu NN#, Wang CK, Chen DY, Sun NH, Lyu H, Körbelin J, Shi WX, Fukunaga K, Lu YM*, Han F*.

Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4

Neuron. 2019 Mar 6;101:920-937.e13 

doi: 10.1016/j.neuron.2018.12.036(IF=14.415)


发表日期:2019

Yu Lei#, Wenming Ren#, Cheng-Kun Wang, Rong-Rong Tao, Huai-Jiang Xiang, Li-Li Feng, Yin-Ping Gao, Quan Jiang, Xin Li*, Youhong Hu*, Feng Han*.

Visualizing Autophagic Flux during Endothelial Injury with a Pathway-Inspired Tandem-Reaction Based Fluorogenic Probe

Theranostics. 2019 Aug 1;9(19):5672-5680

doi: 10.7150/thno.33867(IF=8.698)


发表日期:2019

Dan-Yang Chen#, Ning-He Sun#, Ya-Ping Lu, Ling-Juan Hong, Tian-Tian Cui, Cheng-Kun Wang, Xing-Hui Chen, Shuai-Shuai Wang, Li-Li Feng, Wei-Xing Shi, Kohji Fukunaga, Zhong Chen*, Ying-Mei Lu*, Feng Han*.

GPR124 facilitates pericyte polarization and migration by regulating the formation of filopodia during ischemic injury

Theranostics. 2019 Aug 14;9(20):5937-5955

doi: 10.7150/thno.34168 (IF=8.698)


发表日期:2019

Nan-Nan Lu, Chao Tan(共一), Ning-He Sun, Ling-Xiao Shao, Xiu-Xiu Liu, Yin-Ping Gao, Rong-Rong Tao, Quan Jiang, Cheng-Kun Wang, Ji-Yun Huang, Kui Zhao, Guang-Fa Wang, Zhi-Rong Liu, Kohji Fukunaga, Ying-Mei Lu* and Feng Han*.

Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function

Cereb Cortex. 2018 Jul 1;28(7):2391-2404

doi: 10.1093/cercor/bhx141(IF=5.221)

发表日期:2018

Lu Lu, Zhou-yue Wu, Xin Li and Feng Han*.

State-of-the-art: functional fluorescent probes for bioimaging and pharmacological research

Acta Pharmacol Sin. 2019 Jun;40(6):717-723

doi: 10.1038/s41401-018-0190-8(IF=3.912)

发表日期:2018

Quan Jiang,  Yinping Gao(共一),  Chengkun Wang, Rongrong Tao, Yan Wu, Kaiyu Zhan, Meihua Liao, Nannan Lu, Yingmei Lu, Christopher S. Wilcox, Jianhong Luo, Lin-Hua Jiang*, Wei Yang*, and Feng Han*.

Nitration of TRPM2 as a Molecular Switch Induces Autophagy During Brain Pericyte Injury

Antioxid Redox Signal. 2017 Dec 1;27(16):1297-1316

doi: 10.1089/ars.2016.6873(IF=6.257)

发表日期:2017

Cheng-Kun Wang, Juan Cheng(共一), Xing-Guang Liang, Chao Tan, Quan Jiang, Yong-Zhou Hu, Ying-Mei Lu, Kohji Fukunaga, Feng Han* and Xin Li*.

A H2O2-Responsive Theranostic Probe for Endothelial Injury Imaging and Protection

Theranostics. 2017 Aug 23;7(15):3803-3813

doi: 10.7150/thno.21068(IF=9.129)

发表日期:2017

Xing-Guang Liang, Bo Chen(共一), Ling-Xiao Shao, Juan Cheng, Ming-Zhu Huang, Yu Chen, Yong-Zhou Hu, Yi-Feng Han, Feng Han* and Xin Li*.

A Fluorogenic Probe for Ultrafast and Reversible Detection of Formaldehyde in Neurovascular Tissues

Theranostics. 2017 Jun 1;7(8):2305-2313

doi: 10.7150/thno.19554(IF=9.129)

发表日期:2017

Shiyi Shao, Bo Chen(共一), Juan Cheng, Chengkun Wang, Yanli Zhang, Lingxiao Shao, Yongzhou Hu, Yifeng Han, Feng Han*, Xin Li*.

A fluorogenic probe for imaging protein S-nitrosylation in live cells

Biosens Bioelectron. 2017 Aug 15;94:162-168

doi: 10.1016/j.bios.2017.02.050(IF=7.83)

发表日期:2017

Ling-juan Hong & Quan Jiang(共一) & Sen Long & Huan Wang & Ling-di Zhang & Yun Tian & Cheng-kun Wang & Jing-jing Cao & Rong-rong Tao & Ji-yun Huang & Mei-hua Liao & Ying-mei Lu & Kohji Fukunaga & Nai-ming Zhou* & Feng Han*.

Valproic Acid Influences MTNR1A Intracellular Trafficking and Signaling in a β-Arrestin 2-Dependent Manner

Mol Neurobiol. 2016 Mar;53(2):1237-1246

doi: 10.1007/s12035-014-9085-y(IF=4.336)

发表日期:2016

Xiao-Juan Wang, Yin-Ping Gao, Nan-Nan Lu(共一), Wei-Shuo Li, Ji-Fang Xu, Xiao-Ying Ying, Gang Wu, Mei-Hua Liao, Chao Tan, Ling-Xiao Shao, Ying-Mei Lu, Chen Zhang, Kohji Fukunaga, Feng Han*, and Yong-Zhong Du*.

Endogenous Polysialic Acid Based Micelles for Calmodulin Antagonist Delivery against Vascular Dementia

ACS Appl Mater Interfaces. 2016 Dec 28;8(51):35045-35058

doi: 10.1021/acsami.6b13052(IF=7.861)

发表日期:2016

Xin Li, Rong-Rong Tao(共一), Ling-Juan Hong, Juan Cheng, Quan Jiang, Ying-Mei Lu, Mei-Hua Liao, Wei-Feng Ye, Nan-Nan Lu, Feng Han*, Yong-Zhou Hu*, and You-Hong Hu*.

Visualizing Peroxynitrite Fluxes in Endothelial Cells Reveals the Dynamic Progression of Brain Vascular Injury

J Am Chem Soc. 2015 Sep 30;137(38):12296-303

doi: 10.1021/jacs.5b06865(IF=13.954)

发表日期:2015

Huan Wang, Ling-Juan Hong, Ji-Yun Huang(共一), Quan Jiang, Rong-Rong Tao, Chao Tan, Nan-Nan Lu, Cheng-Kun Wang, Muhammad M Ahmed, Ying-Mei Lu, Zhi-Rong Liu, Wei-Xing Shi, En-Yin Lai, Christopher S Wilcox*, Feng Han*.

P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyteendothelial adhesion and promotes neurovascular injury during septic encephalopathy 

Cell Res. 2015 Jun;25(6):674-90

doi: 10.1038/cr.2015.61(IF=15.393)

发表日期:2015